Wieringen, W.N. van

Research Statement

The study of biological processes in the cell has been revolutionized by the advent of high-throughput techniques. Such techniques generate complex experimental data from various aspects of the cell, e.g., gene expression, mass spectrometry, ChiP-on-chip. Sound statistical methodology for the analysis of these data is imperative for the understanding of the molecular mechanisms underlying the data. In this field of molecular biostatistics I work on the design and analysis of copy number, gene expression, methylation and microRNA microarray experiments. A special focus of my research is the integrative analysis of data from these platforms.